How can I tell if a product has titanium dioxide in it? How can I avoid the ingredient?

In a study published in 2022 in the journal Particle and Fibre Technology, researchers examined the impact of maternal exposure to titanium dioxide nanoparticles in newborn offspring mice. They found that “a chronic exposure to TiO2 NPs during pregnancy alters the respiratory activity of offspring, characterized by an abnormally elevated rate of breathing.” Breathing was also shown to be “significantly and abnormally accelerated,” and the ability for neural circuitry to effectively adjust breathing rates was impaired. The researchers concluded: “Our findings thus demonstrate that a maternal exposure to TiO2 NPs during pregnancy affects the normal development and operation of the respiratory centers in progeny.”

The Colour of Barium Sulphate and Its Suppliers

But that depends on how titanium dioxide is being used and how you might come into contact with it. The International Agency for Research on Cancer (IARC) has classified titanium dioxide as possibly carcinogenic to humans based on studies that showed more lung tumors in rats associated with breathing in titanium dioxide.

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Other scientists, however, have called into question the experimental designs of such studies, citing inconsistent results specifically in studies used to test DNA damage.

Source: Tranalysis and China Customs

EFSA's evaluation is related to the risks of TiO₂ used as a food additive, not to other uses.

The basic scenario of resistive switching in TiO₂ (Jameson et al., 2007) assumes the formation and electromigration of oxygen vacancies between the electrodes (Baiatu et al., 1990), so that the distribution of concomitant n-type conductivity (Janotti et al., 2010) across the volume can eventually be controlled by an external electric bias, as schematically shown in Figure 1B. Direct observations with transmission electron microscopy (TEM) revealed more complex electroforming processes in TiO₂ thin films. In one of the studies, a continuous Pt filament between the electrodes was observed in a planar Pt/TiO₂/Pt memristor (Jang et al., 2016). As illustrated in Figure 1C, the corresponding switching mechanism was suggested as the formation of a conductive nanofilament with a high concentration of ionized oxygen vacancies and correspondingly reduced Ti³⁺ ions. These ions induce detachment and migration of Pt atoms from the electrode via strong metal–support interactions (Tauster, 1987). Another TEM investigation of a conductive TiO₂ nanofilament revealed it to be a Magnéli phase Ti_nO_2n−1 (Kwon et al., 2010). Supposedly, its formation results from an increase in the concentrations of oxygen vacancies within a local nanoregion above their thermodynamically stable limit. This scenario is schematically shown in Figure 1D. Other hypothesized point defect mechanisms involve a contribution of cation and anion interstitials, although their behavior has been studied more in tantalum oxide (Wedig et al., 2015; Kumar et al., 2016). The plausible origins and mechanisms of memristive switching have been comprehensively reviewed in topical publications devoted to metal oxide memristors (Yang et al., 2008; Waser et al., 2009; Ielmini, 2016) as well as TiO₂ (Jeong et al., 2011; Szot et al., 2011; Acharyya et al., 2014). The resistive switching mechanisms in memristive materials are regularly revisited and updated in the themed review publications (Sun et al., 2019; Wang et al., 2020).

Overall, the precipitation of titanium dioxide is a complex process that requires careful control of various factors to achieve the desired product properties. By optimizing the precipitation percentage and carefully monitoring the precipitation process, manufacturers can produce high-quality titanium dioxide that meets the stringent requirements of their customers in the paints, coatings, plastics, and cosmetics industries.

We apply titanium dioxide to our skin through sunscreens, makeup, lip balms, nail polish, and other cosmetic products. 

Edelweiss, 14.5 per cent zinc sulphide, 84 per cent barium sulphate, 1.5 per cent carbonate of lime.

Titanium dioxide (TiO₂) is a naturally occurring mineral that is mined from the earth, processed and refined, and added to a variety of foods, as well as other consumer products. White in color, it is used to enhance the color and sheen of certain foods and is also key for food safety applications. In its natural state it exists in different bulk crystalline forms, such as anatase and rutile, but during processing it is ground into a very fine powder.

Lithopone is an inorganic white pigment, obtained from co-precipitation of Zinc sulfide (ZnS) and Barium sulfate (BaSO4). As a white pigment, it acts as a cost-effective alternative for TiO2. Some of the properties of Lithopone include high brightness and performance under UV exposure. Lithopone requires less wetting agent to achieve optimum wetting of its surface. It is commercially graded on the basis of amount of ZnS. Its grades include 28%, 30%, and 60% ZnS. As a comparatively inexpensive white pigment, Lithopone is presently used in various paint formulations, road marking paints, jointing compounds, and putties.

Lithopone is rather nontoxic, due to the insolubility of its components. It has been used in medicine as a radiocontrast agent. Lithopone is allowed to be in contact with foodstuffs in the US and Europe.^[1]