Abstract
Titanium dioxide A1 adopts good oxidation process, composite inorganic coating and organic treatment, and has the characteristics of excellent particle size distribution, high brightness and high weather resistance. It is recommended for high gloss and high weather resistance coatings, inks and outdoor polymer materials.
Sunscreens and cosmetics containing titanium dioxide are generally considered safe since they are mineral-based products. Mineral products are often recommended for acne-prone and sensitive skin. However, there have been some concerns that titanium dioxide may have a negative impact on health.

In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon. There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”
Less frequently, we ingest E171 through liquids such as salad dressing, dairy products, and some artificially colored drinks. However, since E171 is insoluble, manufacturers must use other stabilizers to keep E171 suspended in liquids as an emulsion; otherwise, it will settle to the bottom.
The evidence also suggests that the toxicity of TiO2 particles may be reduced when eaten as part of the diet. This is because proteins and other molecules in a person's diet can bind to the TiO2 particles. This binding alters the physical and chemical properties of the particles, which influences how they interact with cells, tissues and organs.
As the global demand for tires continues to rise, driven by increasing vehicle production and the expansion of the automotive industry, the market for titanium dioxide also experiences growth. Wholesale suppliers of TiO2 play a vital role in ensuring a stable supply chain for tire manufacturers. By sourcing high-quality titanium dioxide from reliable manufacturers, tire producers can maintain consistent product quality and performance standards.
≥99.0
Pure titanium dioxide is a fine, white powder that provides a bright, white pigment. Titanium dioxide has been used for a century in a range of industrial and consumer products, including paints, coatings, adhesives, paper, plastics and rubber, printing inks, coated fabrics and textiles, as well as ceramics, floor coverings, roofing materials, cosmetics, toothpaste, soap, water treatment agents, pharmaceuticals, food colorants, automotive products, sunscreen and catalysts.
What is an exposure route?
Prof Matthew Wright, both a member of the FAF Panel and chair of EFSA’s working group on E 171, said: “Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods we could not rule out a concern for genotoxicity and consequently we could not establish a safe level for daily intake of the food additive.”