Animal studies show exposure to titanium dioxide is linked to immunotoxicity, inflammation and neurotoxicity.
Total zinc and barium sulphate

A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.


Lithopone is the re-discovered white pigment with functional properties suitable for several applications.

Genotoxicity and cytotoxicity
Moreover, lithopone suppliers are expanding their product lines to offer variations of the pigment that meet specific market needs. Some suppliers provide specialized grades of lithopone that are tailored for particular applications, such as high gloss paints or specialty coatings. By offering these tailored solutions, suppliers can help paint manufacturers enhance the performance characteristics of their products, thus gaining a competitive edge in the market.

Furthermore, lithopone is a versatile pigment that can be easily mixed with other coloring agents to create custom shades and finishes. This flexibility allows leather suppliers to meet the diverse needs of their customers and produce a wide range of leather products in different colors and styles. Whether it's a classic black leather jacket or a trendy pastel-colored purse, lithopone can be tailored to suit any design requirements.
R-895:
Titanium dioxide is used in the production of paper and textiles to improve whiteness, brightness, opacity and durability. It’s often used in fabrics, yarns, paper and other fibers.

Although barium sulfate is almost completely inert, zinc sulfide degrades upon exposure to UV light, leading to darkening of the pigment. The severity of this UV reaction is dependent on a combination of two factors; how much zinc sulfide makes up the pigments formulation, and its total accumulated UV exposure. Depending on these factors the pigment itself can vary in shade over time, ranging from pure white all the way to grey or even black. To suppress this effect, a dopant may be used, such as a small amount of cobalt salts, which would be added to the formulation. This process creates cobalt-doped zinc sulfide. The cobalt salts help to stabilize zinc sulfide so it will not have as severe a reaction to UV exposure.
The Colour of Barium Sulphate and Its Suppliers