- The primary concern surrounding the use of TiO2 in food is its potential to be inhaled or ingested. While TiO2 is generally recognized as safe for consumption by the US Food and Drug Administration (FDA), there are some studies that suggest that it may have adverse effects on human health when consumed in large quantities over a long period of time. These studies have linked TiO2 to respiratory problems, such as inflammation and irritation, as well as potential carcinogenic effects.
- In addition to coated papers, titanium dioxide is also used in the production of specialty papers, such as those used for labels, packaging, and security documents. In these applications, titanium dioxide is added to the paper pulp to increase the opacity and brightness of the paper. This helps to create a more professional and appealing appearance for the final product, as well as providing enhanced security features through the use of fluorescent or UV-reactive titanium dioxide particles
titanium dioxide used in paper.




Lithopone B301, Lithopone B311 powder is also called C.I. 77115; Pigment White 5; Barium zinc sulfate sulfide and belongs to Product Categories of Inorganic & organic chemicals; uvcbs-inorganic. Lithopone B301, Lithopone B311 powder is used in water-based paints because of its excellent alkali resistance. It is widely utilized as a whitener and reinforcing agent for rubber and as a filler and whitener for paper. Lithopone B301, Lithopone B311 powder is considered to be poisonous because it is able to liberate hydrogen sulfide upon decomposition by heat, moisture, and acids. When heated to decomposition Lithopone B301, Lithopone B311 powder emits highly toxic fumes of SOx, ZnO, and H2S.
A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.
Research has shown that, when ingested as a food additive, titanium dioxide and its nanoparticles can impact, alter, and/or damage important protective bacteria in the gut, along with the metabolic pathways of gut bacteria.
Scrap zinc or concentrated zinc ores are dissolved in sulfuric acid, the solution is purified and the two solutions are reacted. A heavy mixed precipitate results that is 28 to 30% zinc sulfide and 72 to 70% barium sulfate.

The authority did not identify a safe amount of titanium dioxide that could be consumed.
ZnSO4 – BaS ➔ BaSO4*ZnS
Tio2 Powder CR-930 Titanium Dioxide Free Sample
There is some evidence that ingested titanium dioxide does not completely exit the body. A 2015 review of animal studies and a few human studies suggests titanium dioxide can get absorbed into the bloodstream and expose other organs to damage.
≥99.0

5. Regulatory compliance The MSDS should also include information on regulatory requirements for the safe handling and use of lithopone, including any permits or certifications that may be necessary.
Safety
The global Lithopone market was valued at $169.8 million in 2019, and is projected to reach $218.6 million by 2027, growing at a CAGR of 3.30% from 2020 to 2027.

