This precipitate is not suitable for a pigment until it is filtered, dried, crushed, heated to a high temperature, and quenched in cold water. The second heating in a muffle furnace at 725 C produces crystals of the right optical size.

Why Did Europe Ban Titanium Dioxide?

In short, no, research demonstrates that E171 is safe when consumed in normal situations.

Moreover, how we're exposed to an ingredient matters significantly in terms of our health and potential toxicity.   

Research shows that inhaling titanium dioxide particles in significant quantities over time can cause adverse health outcomes. Unless you work in an industrial setting, inhaling substantial amounts of titanium dioxide is highly unlikely. 

Research supports that applying titanium dioxide to the skin in the form of sunscreens, makeup, and other topical products does not pose a health risk. 

Overwhelmingly, research that's relevant to human exposure shows us that E171 is safe when ingested normally through foods and drugs (1,2).

Again, other research suggests that E171 could cause harm; however, those research processes did not design their studies to model how people are exposed to E171. Research that adds E171 to drinking water, utilizes direct injections, or gives research animals E171 through a feeding apparatus is not replicating typical human exposure, which occurs through food and medicine consumption.

Read more in-depth about the titanium dioxide risk at go.msu.edu/8Dp5. 

Lithopone 30% CAS No. 1345-05-7 / Nature and stability

Un pigment apparenté, mais où le sulfate de baryum est remplacé par du sulfate de calcium, prend le nom de « sulphopone »

Overall, the Food Directorate's comprehensive review of the available science of TiO₂ as a food additive showed:

In their role as risk managers, the European Commission and Member States will now reflect on EFSA’s scientific advice and decide upon any appropriate regulatory measures or advice for consumers.