
No. EFSA’s role was limited to evaluating the risks linked to titanium dioxide as a food additive. This included an assessment of relevant scientific information on TiO2, its potential toxicity, and estimates of human dietary exposure. Any legislative or regulatory decisions on the authorisations of food additives are the responsibility of the risk managers (i.e. European Commission and Member States).
Wholesale suppliers of lithopone typically offer quotes for bulk orders to businesses and industrial customers. These quotes are based on factors such as quantity, purity, and particle size. When requesting wholesale lithopone MSDS quotes, it is important to consider the following key points
Importance in Factory Settings
Tint reducing power, compared with standard samples
3. Safety measures The MSDS should provide recommendations for safe handling, storage, and disposal of lithopone. This may include guidelines for personal protective equipment, proper ventilation, and spill response procedures.
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TiO2 possesses different qualities depending on whether it is produced as a pigment or a nanomaterial. Both forms are tasteless, odourless and insoluble.


Assessment of skin penetration and biohazard in vivo
Although cosmetics are not meant for consumption, there are concerns that titanium dioxide in lipstick and toothpaste may be swallowed or absorbed through the skin.
Research supports that applying titanium dioxide to the skin in the form of sunscreens, makeup, and other topical products does not pose any health risks.

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CSPI says it might reconsider its rating if specifications for food-grade titanium dioxide in the U.S. are updated to ensure nanoparticles are minimized, and new studies are conducted to assess its capacity to cause cancer or other health problems.
Titanium dioxide makes products, like toothpaste, white and bright. It's also used in makeup, sunscreen, plastic, and paint. (Photo Credit: iStock/Getty Images)
Numerous studies have linked titanium dioxide to genotoxicity and cytotoxicity. Genotoxicity refers to a chemical’s potential to cause DNA damage, which can, in turn, lead to cancer. Cytotoxicity is a general term that refers to a characteristic of being harmful to cells.
All food businesses currently using titanium dioxide as a food additive have a legal responsibility to comply with the requirements of Regulation (EU) 2022/63, banning the use of titanium dioxide. The FSAI encourages food businesses to source suitable alternatives to titanium dioxide and start the process of reformulation now to ensure compliance in advance of the ban coming into force on 7 August 2022.
We even use titanium dioxide when brushing our teeth as it’s found in many toothpastes.